Projects

WASP
WASP

A python-based software designed for comprehensive organism annotation at the whole-proteome level based on structural homology.

Jul 10, 2024

Modelling Intra-Axonal Heterogeneity
Modelling Intra-Axonal Heterogeneity

Investigating the impact of myelination variations along a single axon on action potential (AP) conduction. Summary Background Myelination is crucial for rapid and efficient nerve signal propagation. Traditional models assume uniform myelination, but recent findings suggest significant variability along axons.

Jul 1, 2022

Sounds Classification in the Brainstem
Sounds Classification in the Brainstem

Evaluating various ML methods in classifying sound categories based on fMRI data from brainstem regions. Summary Background The auditory system processes sound through several neuronal structures, with increasing complexity as the signal moves from the cochlea to the auditory cortex.

Jun 3, 2022

Isobutanol Tolerance in S. cerevisiae
Isobutanol Tolerance in S. cerevisiae

Investigating pathways associated with isobutanol tolerance in S. cerevisiae to enhance biofuel production. Summary Background The research focuses on identifying pathways associated with isobutanol tolerance in the yeast strain Saccharomyces cerevisiae.

Jun 1, 2022

MAGNET_GX
MAGNET_GX

RNA-sequencing dataset analysis and metabolic pathway analysis of patients with dilated cardiomyopathy. Summary Background Dilated cardiomyopathy (DCM) is a heart condition characterised by dilation of the left or both ventricles, resulting in a weakened heart muscle and reduced pumping ability.

Feb 1, 2022

Phenotype-Driven Variant Prioritisation Tools
Phenotype-Driven Variant Prioritisation Tools

Evaluation of computational tools for phenotype-driven variant prioritisation in Whole Exome Sequencing data. Summary Background Mitochondrial disorders, particularly hereditary optic neuropathies (HON), have a complex genetic basis that is often difficult to decipher.

Mar 21, 2021

Hemoglobin Complex Analysis
Hemoglobin Complex Analysis

Computational analysis of structural properties of the hemoglobin complex. Summary Background The report provides a comprehensive computational analysis of the hemoglobin complex, focusing on its structural properties and interactions within the human proteome.

Feb 14, 2020